This is a story about Michael (CHRISTIAN ULMEN) and Bruno (MORITZ BLEIBTREU). Though half-brothers, the two are completely different. They share only a mother (NINA HOSS) in common who neglected them to lead a carefree jet-set life leaving them in the care of separate grandparents. Introverted molecular biologist Michael is so wrapped up in his genetic research that he shies away from intimacy while Bruno is a slave to his fantasies paying for sexual favors. Everything changes when both men, now thirty-something, find love. Michael happens to re-unite with his childhood sweetheart, Annabelle (FRANKA POTENTE) and Bruno meets Christiane (MARTINA GEDECK) who shares and enjoys his sexual obsessions. Although it seems that luck is finally on their side, by a cruel twist of fate shatters their happiness.